5-MTHF (Folic Acid) 1 mg 60 Capsules
5-MTHF (Folic Acid) 1 mg 60 Capsules

5-MTHF (Folic Acid) 1 mg 60 Capsules

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Brand: Thorne Research
Style: 110522
Our Price: $17.95
 
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 5-MTHF is the most biologically active form of the B-vitamin folic acid. 5MTHF 
works in concert with vitamin B12 (methylcobalamin) in the conversion of 
homocysteine to methionine, which provides methyl groups for numerous 
other biochemical reactions in the body. Because of this, folate supplementation 
supports cardiovascular health, nervous system function, normal cellular proliferation, 
and gingival health. Folate supplementation during pregnancy has been shown to 
reduce the risk of neural tube defects. 

Research has shown a subset of individuals do not efficiently convert folic acid from 
the diet or supplements to active 5-MTHF, due to genetic enzyme deficiencies. 
Research suggests 5-MTHF is a more efficient form of supplementation than inactive 
folic acid in these and other individuals. 
 
Each Capsule Contains    
Folate (as 5-methyl-tetrahydrofolate)  1000 mcg 
 
Other Ingredients: 
Microcrystalline Cellulose, Hypromellose (derived from cellulose) capsule, Leucine, 
Silicon Dioxide.

*This product uses Gnosis S.p.A.'s L-5-Methyltetrahydrofolate (Extrafolate-SŪ). 
Extrafolate-S is a registered trademark of Gnosis S.p.A. 

Suggested Use: Take 1 capsule two to three times daily or as recommended by a 
health-care practitioner. 

ALLERGY WARNING
This product is contraindicated in an individual with a history of hypersensitivity to 
any of its ingredients.

PURITY
This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, 
or artificial colors, artificial sweeteners, or artificial flavors. This product also does 
not contain lactose, palmitic acid, magnesium stearate, or stearic acid.

PREGNANCY WARNING
If pregnant, consult your health-care practitioner before using this product.

INTERACTIONS
5-methyltetrahydrofolate (5-MTHF) supplementation is not recommended concurrent 
with methotrexate cancer therapy, as it can interfere with methotrexate's anti-neoplastic 
activity; however, this folate source has not been shown to interfere with the anti-
inflammatory activity of methotrexate. An individual taking methotrexate for psoriasis 
or rheumatoid arthritis can safely take a supplement containing folate.





Read Dr. Wright's article on folate
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