Mitochondrial Energy Optimizer with Bio-PQQ™ contains a
broad spectrum of ingredients to counteract the primary factors
of aging while enhancing the ability of mitochondria to produce
energy (ATP). The newest addition, an essential micronutrient
known as PQQ has actually been shown to stimulate the
production of new mitochondria!
This cutting-edge formula provides nutrients to counteract
mitochondrial decay (one of the primary factors of aging),
nutrients to boost the mitochondrial energy-producing capacity,
and now, PQQ. Research has confirmed that PQQ's
cell-signaling effects translate to benefits for the cardiovascular,
nervous, reproductive and immune systems.
Mitochondrial Energy Optimizer is designed to counteract
age-related structural and functional changes by providing
the following unique ingredients:
1. Carnosine : As humans age, their proteins become
irreversibly damaged by lethal glycation reactions. Glycation
is the cross-linking of proteins and sugar to form non-functioning
structures in the body, which can lead to alterations of normal
cell function. Carnosine is not only the premier anti-glycating
agent, but it also protects neurons against reactive and
cytotoxic protein carbonyl species associated with normal aging.
2. Luteolin : Unremitting systemic inflammation is involved with
virtually every undesirable consequence of aging. Culprits behind
chronic inflammatory reactions are pro-inflammatory cytokines,
such as interleukin-1 and tumor necrosis factor alpha. Luteolin is
a super-potent plant extract that has been shown to suppress
these dangerous inflammatory cytokines.
3. Benfotiamine : Benfotiamine blocks multiple destructive
biochemical pathways, including AGEs' formation pathway,
which is induced by higher than desirable blood glucose levels.
Human mortality studies indicate that ideal fasting glucose levels
are between 74 - 85 mg/dL. Yet many aging people have fasting
glucose above 90 mg/dL, which is less than optimal.Benfotiamine
can activate glucose metabolism and promote already healthy
blood glucose levels. In addition, benfotiamine exhibits direct
antioxidative capacity and prevents induction of DNA damage.
4. Pyridoxal 5'-phosphate : Aging results in the formation of toxic
advanced glycation end products throughout the body. Pyridoxal
5'-phosphate is the active form of vitamin B6 that has been shown
to protect against both lipid and protein glycation reactions.
5. R-lipoic acid : Destructive free radical activity in the mitochondria
plays a major role in the loss of cellular vitality. The microencapsulated
Bio-Enhanced® R-lipoic acid facilitates youthful mitochondrial energy
output while guarding against free radicals. Two forms of lipoic acid
are sold on the supplement market, but R-lipoic acid is far more potent.
6. Acetyl-L-carnitine arginate : The amino acid L-carnitine is required to
transport fats into the mitochondria to be burned for cellular energy.
ArginoCarn® Acetyl-L-carnitine arginate is a patented form of carnitine
that has been shown in cell cultures to stimulate the growth of neurites.
7. BioPQQ™ : The newest addition to Mitochondrial Energy Optimizer.
While all the other nutrients in this formula support the structure or function
of mitochondria, PQQ has been shown to stimulate the production of new
mitochondria. In humans, PQQ has been shown to support healthy levels
of CRP and plasma antioxidant potential, as well as to promote memory,
attention, and cognition in maturing individuals. In animals, it has
demonstrated the ability to support cardiovascular, immune, neurological,
and reproductive health.
Serving Size 4 capsules
Servings Per Container 30
Amount Per Serving
Vitamin B6 (as pyridoxal 5'-phosphate) 100 mg
Sodium 25 mg
Carnosine 1000 mg
ArginoCarn® Acetyl-L-carnitine arginate dihydrochloride
Benfotiamine 150 mg
R-Lipoic Acid (as microencapsulated Bio-Enhanced®
stabilized Na-RALA sodium R-lipoate) 150 mg
BioPQQ™ Pyrroloquinoline quinone disodium salt 10 mg
Luteolin (high purity luteolin as Pureolin™) 8 mg
Other ingredients: gelatin, vegetable stearate, silica.
Bio-Enhanced® is a registered trademark of Geronova
Pureolin™ is a trademark of Pharma Science Nutrients, Inc.,
and is used here under license. All rights reserved worldwide.
BioPQQ™ is a trademark of MGC (Japan).
ArginoCarn® is a registered trademark of Sigma-tau Health
Sciences, Inc. and is protected by US patents 6,365,622,
US 6,703,042 and EP1202956.
Dosage and Use
Take two capsules twice daily, preferably early in the day
or all at once upon wakening, or as recommended by a
This product can be taken with or without food.
Life Extension LEF Mitochondrial Energy Optimizer