SAM-e 400mg 30 Tablets

SAM-e 400 provides a full 400 mg SAM-e (net yield) 
from 800 mg of SAM-e tosylate disulfate. SAM-e 400 
is manufactured under low temperature and low 
humidity and is enteric-coated to ensure a biologically 
active product.



Found in all living cells, SAM-e is a metabolite of 
methionine (an essential amino acid). SAM-e is a 
chiral molecule and consists of two forms: (S,S) 
SAM-e and (R,S) SAM-e.  The biologically active 
form is the (S,S) structure, while the (R,S) structure 
is biologically inactive.  Jarrow FORMULAS® 
SAM-e is madenaturally by microbiological fermentation 
and then specially processed without solvents to 
preserve 68-80% (S,S) SAM-e, the highest active 
level available.SAM-e has been clinically shown to 
have the following benefits: 

Joint Strength

SAM-e supports the production of healthy connective 
tissue through transulfuration. In this process, critical 
components of connective tissue, including glucosamine 
and the chondroitin sulfates, are sulfated by 
SAM-e metabolites.*

Brain Metabolism

SAM-e methylation reactions are involved in the synthesis 
of neurotransmitters such as L-DOPA, dopamine and 
related hormones, serotonin, epinephrine and 
phosphatidylcholine (a component of lecithin).* 

Longevity

Methylation of DNA appears to be important in the 
suppression of errors in DNA replication. Demethylation 
of DNA is considered a contributor to the aging process. 
Proper methylation through substances such as SAM-e 
positively influences longevity.* 

Liver

SAM-e metabolism supports the synthesis of glutathione 
(GSH) and glutathione-dependent enzymes (glutathione 
peroxidase and glutathione-S-transferase), which are 
substances important for liver function.* 

Other Ingredients 
Microcrystalline cellulose, silicon dioxide, glycerol 
behenate, magnesium stearate (vegetable source), 
enteric coating (methacrylate copolymers), titanium 
dioxide, magnesium silicate, triethylcitrate, riboflavin, 
glycerol palmitostearate, medium chain triglycerides, 
and carboxymethylstarch sodium salt.

Suitable for vegetarians/vegans.

No wheat, no gluten, no soybeans, no dairy, no egg, 
no fish/shellfish, no peanuts/tree nuts.

This product complies with the proposed USP 
Monograph for SAM-e.

Suggested dose:
Take 1 tablet per day on an empty stomach, or as 
directed by your qualified health care consultant.  

WARNING: Individuals using prescribed medications 
such as antidepressants, including Selective Serotonin 
Re-Uptake Inhibitors (SSRIs) and MAO Inhibitors 
should consult a physician before using. Individuals 
with Parkinson's disease, bi-polar disorder or manic 
depression should not use SAM-e.

Jarrow FORMULAS® SAM-e 400 is foil blister-packed 
to maximize stability and safety. DO NOT use if  outer 
seal of blister pack is broken.







PRODUCT OF ITALY.

Store in a cool, dry place.

Keep out of the reach of children.

send to a friend

print notes